On October 19, the US State Department issued a "worldwide caution security alert" for its citizens abroad due to concerns about potential attacks and increased tensions in various locations worldwide. The advisory urged US citizens overseas to exercise increased caution and stay vigilant, especially in tourist areas. Additionally, it recommended that they sign up to receive information and alerts.

Furthermore, a US State Department official named Josh Paul resigned from the agency over a policy disagreement concerning the US's continued lethal assistance to Israel amid the ongoing conflict with Hamas. He expressed his belief that the current approach, which includes American support for the response by Israel and the status quo of the occupation, would lead to more suffering for both Israelis and Palestinians and was not in the long-term American interest.